Item Classification List

  1. Basic Science
    1. Immune mechanisms
      1. Antigens / Antigen Presentation/Superantigens
      2. Major Histocompatibility Complex
      3. Immunoregulation / Tolerance
      4. Immunogenetics / Molecular Biology
      5. Immunoglobulins (including IgE)
      6. T and B Cell Ligand-Receptor Interactions and Signal Transduction / Cell Activation / Anergy
      7. Cytokines / Chemokines and Their Receptors
      8. Adhesion Molecules
      9. Complement / Kinins
      10. Mucosal Immunity
      11. Transplantation / Tumor immunology
      12. Innate Immunity/TLRs
    2. Cells Involved in Immune Responses (Differentiation, Origin, Reception, Interactions, Secretions)
      1. Lymphocytes
        1. T cells
        2. B cells
        3. NK cells
        4. LAK cells
      2. Monocytes / Macrophages / Dendritic Cells (i.e., Antigen-Presenting Cells)
      3. Mast Cells / Basophils
      4. Eosinophils
      5. Neutrophils
      6. Platelets
      7. Endothelial / Epithelial / Smooth Muscle / Fibroblasts
    3. Specific Immune Responses
      1. Immediate Hypersensitivity (IgE-Mediated)
        1. IgE Receptor / Allergen Binding
        2. Biochemical Events
        3. Preformed Mediator Release
        4. Lipid Mediators
        5. Modulation of Mediator Release
        6. Cytokines
        7. Effect of Mediators on Target Organs
        8. Role of Eosinophils & Neutrophils
        9. Early / Late-Phase Reactions
      2. IgG/IgA/IgM-Mediated Reactions
        1. Opsonization
        2. Complement Fixation & Fcg Receptor Activation
        3. Antibody-Dependent Cell-Mediated Cytotoxicity
        4. Antibody-Mediated Immune Regulation
      3. Immune Complex- Mediated
      4. Cell-mediated
        1. CD4+ Cells (TH1, TH2) and T regulatory cells
        2. CD8+ Cells
        3. NK / NKT Cells
    4. Laboratory Tests
      1. Ig Measurement / Total & Specific
      2. Mediator Measurement
      3. Cell Surface Markers and Receptors (Flow Cytometry)
      4. Lymphocyte Function: Proliferation, Cytotoxicity
      5. Chemotaxis
      6. Phagocytosis / Killing
      7. Hybridoma / Monoclonal Antibodies
      8. Immune Complexes
      9. Complement
      10. Molecular Biology Technology including TRECs. RTPCR, in situ hybridization, cell purification, gene chips
      11. Intracellular Signaling/Mediator Detection
    5. Anatomy / Physiology / Pathology
      1. Lymphoid System & Organs
      2. Upper Airway, Nose, Sinuses, Middle Ear
      3. Lower Airway (Remodeling)
      4. Skin
      5. Gastrointestinal
    6. Research Principles
      1. Experimental Design
      2. Data Analysis and Biostatistics
      3. Epidemiology
      4. Informed Consent
      5. Adverse Event Reporting
  2. Clinical Science
    1. Hypersensitivity Disorders
      1. Rhinitis
        1. Epidemiology and Risk Factors
        2. Pathogenesis
        3. Diagnostic Criteria
        4. Differential Diagnosis
        5. Treatment
      2. Sinusitis
        1. Epidemiology and Risk Factors
        2. Pathogenesis
        3. Diagnostic Criteria
        4. Differential Diagnosis
        5. Treatment
      3. Otitis
      4. Conjunctivitis
        1. Epidemiology and Risk Factors
        2. Pathogenesis
        3. Diagnostic Criteria
        4. Differential Diagnosis
        5. Treatment
      5. Eczema / Atopic Dermatitis
        1. Epidemiology and Risk Factors
        2. Pathogenesis
        3. Diagnostic Criteria
        4. Differential Diagnosis
        5. Treatment
      6. Asthma
        1. Children
          1. Epidemiology and Risk Factors
          2. Pathogenesis
          3. Diagnostic Criteria
          4. Differential Diagnosis
          5. Treatment
        2. Adults
          1. Epidemiology and Risk Factors
          2. Pathogenesis
          3. Diagnostic Criteria
          4. Differential Diagnosis
          5. Treatment
      7. Occupational Diseases
      8. ABPA / AFS
      9. Hypersensitivity Pneumonitis
      10. Interstitial Pneumonitis
      11. COPD
      12. Food Allergy
        1. Epidemiology and Risk Factors
        2. Pathogenesis
        3. Diagnostic Criteria
        4. Differential Diagnosis
        5. Treatment
      13. Anaphylaxis (including Idiopathic, Exercise, Latex)
        1. Epidemiology and Risk Factors
        2. Pathogenesis
        3. Diagnostic Criteria
        4. Differential Diagnosis
        5. Treatment
      14. Stinging Insect Allergy
        1. Epidemiology and Risk Factors
        2. Pathogenesis
        3. Diagnostic Criteria
        4. Differential Diagnosis
        5. Treatment
      15. Drug Reactions
        1. Epidemiology and Risk Factors
        2. Pathogenesis
        3. Diagnostic Criteria
        4. Differential Diagnosis
        5. Treatment
      16. Urticaria
        1. Epidemiology and Risk Factors
        2. Pathogenesis
        3. Diagnostic Criteria
        4. Differential Diagnosis
        5. Treatment
      17. Contact Hypersensitivity
      18. Vaccine (Principles and Reactions)
      19. Bronchiolitis
      20. Croup
    2. Immunological Disorders
      1. Hereditary and Acquired Angioedema
      2. Congenital (Primary) Immunodeficiencies
        1. Complement Deficiencies
        2. Neutrophil Deficiencies
        3. T Cell Deficiencies
        4. B Cell / Antibody Deficiencies
      3. Acquired (Secondary) Immunodeficiencies
        1. HIV/AIDS-related
        2. Non-HIV/AIDs-related
      4. Systemic Autoimmune Disease
        1. RA
        2. SLE
        3. Vasculitis
        4. Other Disorders
      5. Immunologic Rejection / Organ Transplantation
      6. Stem Cell Transplantation (Bone Marrow, Cord Blood, etc.)
      7. Graft vs. Host Reaction
      8. Immune Endocrinopathies (Thyroid, Diabetes, Adrenal)
      9. Immunologic Renal Diseases
      10. Immunologic Skin Diseases
      11. Immunologic Eye Diseases
      12. Inflammatory Gastrointestinal Diseases
      13. Immunologic Neuropathies
      14. Hypereosinophilic Syndromes
      15. Leukemias, Lymphomas, Myelomas
      16. Granulomatous Diseases
        1. Sarcoidosis
        2. Wegner Granulomatosis
      17. Amyloidosis
      18. Mastocytosis
      19. Immunohematologic Diseases
      20. Cystic Fibrosis
      21. Reproductive Immunology
      22. Immunologic Aspects of Infectious Diseases (Lyme Disease, TB, Leprosy, Hepatitis, Syphilis)
    3. Pharmacology / Therapeutics
      1. Allergen Avoidance
      2. Immunotherapy
      3. Histamine Antagonists
      4. Theophylline
      5. Beta-Agonists and Antagonists
      6. Leukotriene Pathway Modulators
      7. Mast Cell Stabilizers
      8. Anticholinergics
      9. Glucocorticoids
      10. Immunomodulators / Suppressives (including anti-IgE, DNA,CpG ODNs)
      11. Immunoglobulin Replacement Therapy
      12. Cytokine and Cytokine Receptor-Mediated Therapy (IFNs, CSFs, ILs)
      13. Cellular Immune Reconstitution
      14. Immunoprophylaxis Vaccine
      15. Apheresis
      16. Anti-inflammatory Agents (including COX-1 & 2)
      17. Surgical Intervention with Sinuses / Middle Ear
      18. Controversial Treatments
      19. Cardiopulmonary Resuscitation
      20. Dermatologic and Ophthalmic Treatments
      21. Gene Transfer
    4. Specific Diagnostic Modalities
      1. Skin tests (Immunoassay for Total and Specific IgE)
      2. Nasal Provocation
      3. Pulmonary Function Tests
      4. Bronchial Provocation
      5. Nasal and Sputum Smears
      6. Mucociliary Function
      7. Serologic Tests
        1. ELISA
        2. Western Blot
      8. Serologic Tests for Autoimmunity
      9. Molecular Diagnostics / Tissue Typing
      10. Imaging
      11. Flow Cytometry / Cell Surface Markers
      12. Controversial Tests / Misuse of Standard Tests
      13. Delayed Type Hypersensitivity Tests
      14. Food Challenge
    5. Allergens / Antigens
      1. Pollens
      2. Molds and Fungi
      3. Indoor Allergens
      4. Animal Proteins
      5. Pollutants
      6. Standardization of Antigens
      7. Stability of Antigens
      8. Environmental Controls
      9. Aerobiology
      10. Autoantigens
      11. Infectious Agents
      12. Foods
      13. Venoms

    Updated: 7/24/2008



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